Voluntary Trading Update Aspen Pharmacare Holdings Limited (Incorporated in the Republic of South Africa) (Registration number 1985/002935/06) Share code: APN & ISIN: ZAE000066692 ("Aspen") Voluntary Trading Update Aspen shareholders are hereby advised that normalised headline earnings per share (“NHEPS”), headline earnings per share and earnings per share for the year ended 30 June 2018 are expected to improve on those reported in the prior year ended 30 June 2017, within the following ranges: Measure Range Cents per share Cents per share in the prior year - 30 June 2017 NHEPS 8% to 12% 1580.3 to 1638.8 1463.2 Headline earnings per 11% to 15% 1442.4 to 1494.4 1299.5 share Earnings per share 15% to 19% 1291.9 to 1336.8 1123.4 NHEPS comprises headline earnings per share adjusted for specific non-trading items. NHEPS is the primary measure used by management to assess Aspen’s underlying financial performance. At constant exchange rates, revenue in the second half of the financial year was in line with that of the first half. However, the stronger Rand in the second half resulted in actual reported second half revenue being over a R1 billion lower. This had a consequential unfavourable impact on earnings. The financial results on which this trading announcement is based have not been reviewed or reported on by Aspen’s external auditors. Aspen’s results for the year ended 30 June 2018 are scheduled to be published on SENS on 13 September 2018. Durban 4 September 2018 Sponsor: Investec Bank Limited Date: 04/09/2018 08:00:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.