Change to the Board Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) CHANGE TO THE BOARD The board of directors of Ascendis is pleased to announce the appointment of Mr Johannes George Sebulela as an independent non-executive director with effect from 2 October 2018. George has a BA (Com) from the University of Fort Hare and a Diploma in Marketing. He has completed various leadership and development programmes including, inter alia, the INSEAD Advanced Management Program, The GIBS Leadership Development Programme and Board Development Program, as well as the WBS Principles of Business Management. George is currently the CEO of the Sebvest Group. He holds appointments as a non- executive director on seven boards, is a committee member of the JSE CEO Initiative, Secretary General of the Black Business Council and serves on the South African BRICS Business Council. He is the founder and president of the African Entrepreneurs Council. The board welcomes George and believes that he will bring skills, expertise and experience to the board. 2 October 2018 Johannesburg Sponsor Questco Corporate Advisory Proprietary Limited Date: 02/10/2018 03:40:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.