Posting of Integrated Annual Report, no change statement and notice of Annual General Meeting Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) POSTING OF INTEGRATED ANNUAL REPORT, NO CHANGE STATEMENT AND NOTICE OF ANNUAL GENERAL MEETING POSTING OF INTEGRATED ANNUAL REPORT Ascendis shareholders (“Shareholders”) are advised that the Integrated Annual Report for the year ended 30 June 2018, including summarised consolidated financial statements for the same period and the Notice of Annual General Meeting, have been posted to Shareholders. Copies of the Annual General Meeting notice, the summarised audited financial statements and the complete annual financial statements as at 30 June 2018, are available on the Company’s website with effect from today, Wednesday, 03 October 2018 (https://ascendishealth.com/investor-relations /integrated-reports) or alternatively may be requested: - from the Company’s registered office: 31 Georgian Crescent East, Bryanston, Gauteng, 2191; or - by email: info@ascendishealth.com NO CHANGE STATEMENT Neither the audited annual financial statements referred to herein nor the audit report contain any modifications to the audited results published on SENS on 25 September 2018. NOTICE OF THE ANNUAL GENERAL MEETING Shareholders are advised that the Company’s sixth Annual General Meeting has been convened for 09:00 on Thursday, 08 November 2018, at Ground Floor, Ascendis building, 31 Georgian Crescent East, Bryanston, Gauteng, 2191, to transact the business stated in the Notice of the Annual General Meeting. 2018 Record date for determining those shareholders entitled to receive the Friday, 21 September notice of AGM Last day to trade in order to be eligible to participate in, and vote at the Tuesday, 30 October AGM Record date (for voting purposes at the AGM) Friday, 2 November Participation in the Annual General Meeting will also be facilitated by webcasting and the relevant details appear in the Notice of the Annual General Meeting. Johannesburg 03 October 2018 Sponsor: Questco Corporate Advisory (Pty) Ltd Date: 03/10/2018 02:02:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.