Dealings in securities by an associate of a director Ascendis Health Limited (Registration number 2008/005856/06) (Incorporated in the Republic of South Africa) Share code: ASC ISIN: ZAE000185005 (“Ascendis” or “the Company”) Dealings in securities by an associate of a director In terms of paragraphs 3.63 to 3.74 of the Listings Requirements of the JSE Limited, the following information, relating to dealings in securities by an associate of a director, is disclosed: Director: Gary Shayne Type of director: Non-executive director Name of associate: Gane Holdings Proprietary Limited (“Gane Holdings”) Nature and extent of interest: Indirect beneficial – through Gane Holdings, in which Gary Shayne holds an indirect controlling shareholding through the ultimate holding company, Coast2Coast Communications Limited (“C2C”) Nature of transaction: Sale, off market Gane Holdings has entered into a financing agreement with an institutional lender (“Lender”), in terms of which Gane Holdings will be provided with a loan that is to be secured by pledged Ascendis shares (“Security Shares”). One of the primary purposes of the loan is to fund the purchase of Ascendis shares by C2C. The Security Shares will be transferred to the Lender in tranches for the duration of the financing arrangement. On settlement of the loan, the Security Shares will be returned to Gane Holdings. Date of transaction: 19 October 2018 Class of shares: Ordinary shares Number of shares: Up to a total of 18,000,000 shares, in tranches as and when Gane Holdings elects Price per share: The pricing of each tranche of Security Shares will be determined as the average closing price of shares over the 5 business days ending on a date 5 business days after the date on which that tranche of Security Shares is pledged. This equates to R8.95 per share had the 5 business days ended on 18 October 2018. Value: R161,100,000 in aggregate, assuming a price per share of R8.95 for all tranches Written clearance obtained: Clearance was obtained from the Chairman Bryanston 22 October 2018 Sponsor Questco Corporate Advisory Proprietary Limited Date: 22/10/2018 09:06:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE'). The JSE does not, whether expressly, tacitly or implicitly, represent, warrant or in any way guarantee the truth, accuracy or completeness of the information published on SENS. The JSE, their officers, employees and agents accept no liability for (or in respect of) any direct, indirect, incidental or consequential loss or damage of any kind or nature, howsoever arising, from the use of SENS or the use of, or reliance on, information disseminated through SENS.